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Focus e sonno

Dihexa

Chemical compound

  • FormulaC27H44N4O5
  • Peso molecolare504.7 g/mol
  • Numero CAS1401708-83-5
  • Risultati PubMed18

Scheda 9 di 40Dati recuperati il 2026-10-08.PubChem · PubMed · Wikipedia

Identificazione

Campo di ricercaFocus e sonno
Nome in PubChemN-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide
FormulaC27H44N4O5
Peso molecolare504.7 g/mol
Numero CAS1401708-83-5
Noto anche come9WYX65A5C2, PNB-0408, ATH-1001, RefChem:1090816, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, Hexanoyl-Tyr-Ile-Ahx-NH2, C27H44N4O5, Dihexa (PNB-0408)?, orb1220467, orb1685499
PubChemCID 129010512

In breve

Dihexa is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met.

Mostrata in inglese: in questa lingua Wikipedia non ha una voce sull'argomento.

Da Wikipedia, disponibile con licenza CC BY-SA 4.0. Breve descrizione da Wikidata (CC0).

Ricerca pubblicata

I titoli sono riportati come pubblicati. Elencare un articolo non significa avallarne le conclusioni, e molti lavori sui peptidi da ricerca sono studi di laboratorio o su animali: il tipo di studio è indicato quando PubMed lo registra.

  1. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsReviewRahman OF, Lee SJ, Seeds WA · J Am Acad Orthop Surg Glob Res Rev, 2026 · PMID 41490200 · DOI
  2. Hepatocyte growth factor mimetic protects lateral line hair cells from aminoglycoside exposureUribe PM, Kawas LH, Harding JW et al. · Front Cell Neurosci, 2015 · PMID 25674052 · DOI
  3. The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met systemResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tRetracted PublicationBenoist CC, Kawas LH, Zhu M et al. · J Pharmacol Exp Ther, 2014 · PMID 25187433 · DOI
  4. AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling PathwaySun X, Deng Y, Fu X et al. · Brain Sci, 2021 · PMID 34827486 · DOI
  5. The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's DiseaseResearch Support, Non-U.S. Gov'tReviewWright JW, Harding JW · J Alzheimers Dis, 2015 · PMID 25649658 · DOI
  6. Dimeric DOTA-alpha-melanocyte-stimulating hormone analogs: synthesis and in vivo characteristics of radiopeptides with high in vitro activityResearch Support, Non-U.S. Gov'tBapst JP, Froidevaux S, Calame M et al. · J Recept Signal Transduct Res, 2007 · PMID 18097939 · DOI
  7. Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agentsResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tMcCoy AT, Benoist CC, Wright JW et al. · J Pharmacol Exp Ther, 2013 · PMID 23055539 · DOI
  8. Stem cell, Granulocyte-Colony Stimulating Factor and/or Dihexa to promote limb function recovery in a rat sciatic nerve damage-repair model: Experimental animal studiesWeiss JB, Phillips CJ, Malin EW et al. · Ann Med Surg (Lond), 2021 · PMID 34703584 · DOI

I primi 8 di 18 risultati, per pertinenza. Vedi tutti su PubMed.

Ricerca eseguita "Dihexa"[Title/Abstract]

Provenienza dei dati

DatoFonteRecord
Identità chimica e strutturaPubChemCID 129010512
Letteratura pubblicataPubMedRicerca su PubMed
Frase di presentazioneWikipediaDihexa

Dati recuperati il 2026-10-08. Le fonti sono descritte in Info. Come vengono raccolti e controllati i dati: Metodi.