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Focus and sleep

Semax

Chemical compound

  • FormulaC37H51N9O10S
  • Molecular weight813.9 g/mol
  • CAS number80714-61-0
  • PubMed results208

Reference sheet 33 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Sold for in vitro laboratory research only — not for human or animal consumption. ≥99% purity specification.

Identification

Field of researchFocus and sleep
PubChem nameACTH (4-7), Pro-Gly-Pro-
FormulaC37H51N9O10S
Molecular weight813.9 g/mol
CAS number80714-61-0
Also known asI5FAL2585H, ACTH (4-7), prolyl-glycyl-proline-, Pro-gly-pro-acth (4-7), RefChem:56007, MEHFPGP, Met-Glu-His-Phe-Pro-Gly-Pro, Semax?, H-Met-Glu-His-Phe-Pro-Gly-Pro-OH, orb1705158, C37H51N9O10S
PubChemCID 9811102

Summary

Semax, an abbreviation of "seven amino acids", is a medication which is used in Eastern Europe for the treatment of a broad range of conditions like brain trauma but predominantly for its claimed nootropic, neuroprotective, and neurorestorative effects.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsReviewRahman OF, Lee SJ, Seeds WA · J Am Acad Orthop Surg Glob Res Rev, 2026 · PMID 41490200 · DOI
  2. Functional Connectomic Approach to Studying Selank and Semax EffectsPanikratova YR, Lebedeva IS, Sokolov OY et al. · Dokl Biol Sci, 2020 · PMID 32342318 · DOI
  3. Therapeutic peptides in gerontology: mechanisms and applications for healthy agingReviewMavrych V, Shypilova I, Bolgova O · Front Aging, 2026 · PMID 42021992 · DOI
  4. Gateways to clinical trialsBibliographyBayes M, Rabasseda X, Prous JR · Methods Find Exp Clin Pharmacol, 2005 · PMID 16082427
  5. Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodentsResearch Support, Non-U.S. Gov'tEremin KO, Kudrin VS, Saransaari P et al. · Neurochem Res, 2005 · PMID 16362768 · DOI
  6. Effects of Semax on the Default Mode Network of the BrainLebedeva IS, Panikratova YR, Sokolov OY et al. · Bull Exp Biol Med, 2018 · PMID 30225715 · DOI
  7. Pharmacological Aspects of Neuro-Immune InteractionsResearch Support, Non-U.S. Gov'tReviewTarasov VV, Kudryashov NV, Chubarev VN et al. · Curr Pharm Des, 2018 · PMID 28875850 · DOI
  8. Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female miceLiu R, Chen Y, Huang H et al. · Br J Pharmacol, 2025 · PMID 40692165 · DOI

Top 8 of 208 results, by relevance. See all on PubMed.

Search query "Semax"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 9811102
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaSemax

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.