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Weight research

Mazdutide

GLP1 poly-agonist drug

  • FormulaC207H317N45O65
  • Molecular weight4476 g/mol
  • CAS number2259884-03-0
  • PubMed results51

Reference sheet 24 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

Identification

Field of researchWeight research
FormulaC207H317N45O65
Molecular weight4476 g/mol
CAS number2259884-03-0
Also known asIBI362, GTPL13924, IBI-362, GLXC-26803, compound 1 [US9938335B2], EX-A12490, LY3305677, LY-3305677
PubChemCID 167312357

Summary

Mazdutide is a dual agonist of the GLP-1 receptor and glucagon receptor.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Once-Weekly Mazdutide in Chinese Adults with Obesity or OverweightRandomized Controlled TrialClinical Trial, Phase IIIMulticenter StudyJi L, Jiang H, Bi Y et al. · N Engl J Med, 2025 · PMID 40421736 · DOI
  2. Emerging pharmacotherapies for obesity: A systematic reviewSystematic ReviewKokkorakis M, Chakhtoura M, Rhayem C et al. · Pharmacol Rev, 2025 · PMID 39952695 · DOI
  3. Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysisSystematic ReviewNetwork Meta-AnalysisComparative StudyNong K, Shi Q, Xie X et al. · BMJ, 2026 · PMID 42419792 · DOI
  4. Mazdutide: First ApprovalReviewShirley M · Drugs, 2025 · PMID 41028652 · DOI
  5. Beyond weight loss: multisystem benefits of obesity medicationsReviewSavas M, Kuckuck S, Boon MR et al. · Lancet Diabetes Endocrinol, 2026 · PMID 42208956 · DOI
  6. Novel GLP-1-based Medications for Type 2 Diabetes and ObesityReviewSon JW, le Roux CW, Blüher M et al. · Endocr Rev, 2026 · PMID 41054801 · DOI
  7. Seven glucagon-like peptide-1 receptor agonists and polyagonists for weight loss in patients with obesity or overweight: an updated systematic review and network meta-analysis of randomized controlled trialsSystematic ReviewNetwork Meta-AnalysisResearch Support, Non-U.S. Gov'tXie Z, Zheng G, Liang Z et al. · Metabolism, 2024 · PMID 39305981 · DOI
  8. Efficacy and Safety of Mazdutide in Chinese Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Phase 2 TrialRandomized Controlled TrialClinical Trial, Phase IIResearch Support, Non-U.S. Gov'tZhang B, Cheng Z, Chen J et al. · Diabetes Care, 2024 · PMID 37943529 · DOI

Top 8 of 51 results, by relevance. See all on PubMed.

Search query "Mazdutide"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 167312357
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaMazdutide

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.