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Skin and hair

GHK-Cu

Chemical compound

  • FormulaC14H21CuN6O4-
  • Molecular weight400.90 g/mol
  • PubMed results82

Reference sheet 13 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Identification

Field of researchSkin and hair
PubChem nameCopper tripeptide
FormulaC14H21CuN6O4-
Molecular weight400.90 g/mol
Also known as[N2-(N-Glycyl-L-histidyl)-L-lysinato(2-)]copper, EX-A13486, Gly-His-Lys-Cu(II), Copper Peptide(GHK-Cu)
PubChemCID 139035031

Summary

Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene DataReviewPickart L, Margolina A · Int J Mol Sci, 2018 · PMID 29986520 · DOI
  2. The potential of GHK as an anti-aging peptideDou Y, Lee A, Zhu L et al. · Aging Pathobiol Ther, 2020 · PMID 35083444 · DOI
  3. Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine PhysiciansReviewMayfield CK, Bolia IK, Feingold CL et al. · Am J Sports Med, 2026 · PMID 41476424 · DOI
  4. Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospectiveReviewMortazavi SM, Mohammadi Vadoud SA, Moghimi HR · Bioimpacts, 2025 · PMID 39963574 · DOI
  5. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsReviewRahman OF, Lee SJ, Seeds WA · J Am Acad Orthop Surg Glob Res Rev, 2026 · PMID 41490200 · DOI
  6. Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?ReviewOgórek K, Nowak K, Wadych E et al. · Molecules, 2025 · PMID 39795193 · DOI
  7. Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic PerformanceReviewMendias CL, Awan TM · Sports Med, 2026 · PMID 41966639 · DOI
  8. Peptide Supplements and Their Therapeutic Applications in Sports MedicineTewari K, Liu TP, Im C et al. · Am J Sports Med, 2026 · PMID 42578445 · DOI

Top 8 of 82 results, by relevance. See all on PubMed.

Search query "GHK-Cu"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 139035031
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaCopper peptide GHK-Cu

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.