Available in the shop
- Epithalon 10 mg — $73.50
- Epithalon 50 mg — $294.00
Sold for in vitro laboratory research only — not for human or animal consumption. ≥99% purity specification.
Identification
| Field of research | Anti-ageing research |
|---|---|
| Formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| CAS number | 307297-39-8, 64082-79-7 |
| Also known as | Epithalon, Epithalone, Ala-Glu-Asp-Gly, AE-0 peptide, O65P17785G, alanyl-glutamyl-aspartyl-glycine, RefChem:921052, Epithalamin, Epithalamine, Epithalon? |
| PubChem | CID 219042 |
Summary
Epitalon is a synthetic peptide, telomerase activator, and putative anti-aging compound, which was identified as the putative active component of a bovine pineal gland extract known as epithalamin.
From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).
Published research
Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising PropertiesReviewAraj SK, Brzezik J, Mądra-Gackowska K et al. · Int J Mol Sci, 2025 · PMID 40141333 · DOI
- Peptides and AgeingReviewKhavinson VKh · Neuro Endocrinol Lett, 2002 · PMID 12374906
- Therapeutic peptides in gerontology: mechanisms and applications for healthy agingReviewMavrych V, Shypilova I, Bolgova O · Front Aging, 2026 · PMID 42021992 · DOI
- Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activityResearch Support, Non-U.S. Gov'tAl-Dulaimi S, Thomas R, Matta S et al. · Biogerontology, 2025 · PMID 40908429 · DOI
- The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic RetinopathyResearch Support, Non-U.S. Gov'tGatta M, Dovizio M, Milillo C et al. · Stem Cell Rev Rep, 2025 · PMID 40493162 · DOI
- Epitalon protects against post-ovulatory aging-related damage of mouse oocytes in vitroResearch Support, Non-U.S. Gov'tYue X, Liu SL, Guo JN et al. · Aging (Albany NY), 2022 · PMID 35413689 · DOI
- Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He miceResearch Support, Non-U.S. Gov'tKossoy G, Anisimov VN, Ben-Hur H et al. · In Vivo, 2006 · PMID 16634527
- Epitalon influences pineal secretion in stress-exposed rats in the daytimeSibarov DA, Kovalenko RI, Malinin VV et al. · Neuro Endocrinol Lett, 2002 · PMID 12500171
Top 8 of 63 results, by relevance. See all on PubMed.
Search query "Epitalon"[Title/Abstract]
Data provenance
| Data | Source | Record |
|---|---|---|
| Chemical identity and structure | PubChem | CID 219042 |
| Published literature | PubMed | Search on PubMed |
| Summary sentence | Wikipedia | Epitalon |
Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.