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AOD-9604

Orally active, lipolytic fragment of human growth hormone

  • FormulaC78H123N23O23S2
  • Molecular weight1815.1 g/mol
  • CAS number221231-10-3
  • PubMed results22

Reference sheet 3 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Identification

Field of researchWeight research
FormulaC78H123N23O23S2
Molecular weight1815.1 g/mol
CAS number221231-10-3
Also known asAOD 9604, AOD9604, RefChem:113278, 7UP768IP4M, AOD9604 acetate, orb1910051, EX-A4625, WIA23110, AOD-9604?, AT50792
PubChemCID 71300630

Summary

AOD9604 is an orally active, lipolytic 16-amino acid peptide fragment of human growth hormone and derivative of the C-terminal domain of human growth hormone (HGH).

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsReviewRahman OF, Lee SJ, Seeds WA · J Am Acad Orthop Surg Glob Res Rev, 2026 · PMID 41490200 · DOI
  2. AOD-9604 MetabolicReviewWilding J · Curr Opin Investig Drugs, 2004 · PMID 15134286
  3. Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic PerformanceReviewMendias CL, Awan TM · Sports Med, 2026 · PMID 41966639 · DOI
  4. Detection and in vitro metabolism of AOD9604Research Support, N.I.H., ExtramuralValidation StudyCox HD, Smeal SJ, Hughes CM et al. · Drug Test Anal, 2015 · PMID 25208511 · DOI
  5. Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis ModelKwon DR, Park GY · Ann Clin Lab Sci, 2015 · PMID 26275694
  6. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragmentComparative StudyResearch Support, Non-U.S. Gov'tHeffernan MA, Thorburn AW, Fam B et al. · Int J Obes Relat Metab Disord, 2001 · PMID 11673763 · DOI
  7. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out miceResearch Support, Non-U.S. Gov'tHeffernan M, Summers RJ, Thorburn A et al. · Endocrinology, 2001 · PMID 11713213 · DOI
  8. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormoneNg FM, Sun J, Sharma L et al. · Horm Res, 2000 · PMID 11146367 · DOI

Top 8 of 22 results, by relevance. See all on PubMed.

Search query "AOD9604"[Title/Abstract] OR "AOD-9604"[Title/Abstract] OR "AOD 9604"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 71300630
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaAOD9604

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.