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Weight research

Tirzepatide

Anti-diabetic and anti-obesity medication

  • FormulaC225H348N48O68
  • Molecular weight4813 g/mol
  • PubMed results2,584

Reference sheet 39 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Sold for in vitro laboratory research only — not for human or animal consumption. ≥99% purity specification.

Identification

Field of researchWeight research
FormulaC225H348N48O68
Molecular weight4813 g/mol
Also known asZepbound, tirzepatida, tirzepatidum, OYN3CCI6QE, RefChem:58651, BG-121, GTPL11429, FT181880, FT182420, Tirzepatide sodium salt (LY3298176)?
PubChemCID 156588324

Summary

Tirzepatide is a gastric inhibitory polypeptide (GIP) analog and a GLP-1 receptor agonist.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical TrialClinical Trial, Phase IIIMulticenter StudyRandomized Controlled TrialResearch Support, Non-U.S. Gov'tAronne LJ, Sattar N, Horn DB et al. · JAMA, 2024 · PMID 38078870 · DOI
  2. Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trialsSystematic ReviewNetwork Meta-AnalysisKaragiannis T, Malandris K, Avgerinos I et al. · Diabetologia, 2024 · PMID 38613667 · DOI
  3. Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection FractionComparative StudyObservational StudyKrüger N, Schneeweiss S, Fuse K et al. · JAMA, 2025 · PMID 40886075 · DOI
  4. Tirzepatide: A Review in Type 2 DiabetesReviewFrance NL, Syed YY · Drugs, 2024 · PMID 38388874 · DOI
  5. Tirzepatide as Compared with Semaglutide for the Treatment of ObesityClinical Trial, Phase IIIComparative StudyEquivalence TrialMulticenter StudyAronne LJ, Horn DB, le Roux CW et al. · N Engl J Med, 2025 · PMID 40353578 · DOI
  6. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 DiabetesClinical Trial, Phase IIIComparative StudyEquivalence TrialMulticenter StudyRandomized Controlled TrialResearch Support, Non-U.S. Gov'tFrías JP, Davies MJ, Rosenstock J et al. · N Engl J Med, 2021 · PMID 34170647 · DOI
  7. Tirzepatide for overweight and obesity managementReviewHamza M, Papamargaritis D, Davies MJ · Expert Opin Pharmacother, 2025 · PMID 39632534 · DOI
  8. Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trialClinical Trial, Phase IIIRandomized Controlled TrialRosenstock J, Wysham C, Frías JP et al. · Lancet, 2021 · PMID 34186022 · DOI

Top 8 of 2,584 results, by relevance. See all on PubMed.

Search query "Tirzepatide"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 156588324
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaTirzepatide

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.