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About / Peptides / Thymosin alpha-1

Immunity

Thymosin alpha-1

Protein-coding gene in the species Homo sapiens

  • FormulaC129H215N33O55
  • Molecular weight3108.3 g/mol
  • CAS number62304-98-7
  • PubMed results622

Reference sheet 37 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Identification

Field of researchImmunity
PubChem nameThymalfasin
FormulaC129H215N33O55
Molecular weight3108.3 g/mol
CAS number62304-98-7, 69521-94-4
Also known asThymosin alpha 1, Thymosin alpha1, Zadaxin, alpha1-Thymosin, Thymosin alpha1 (human), thymalfasine, timalfasina, Thymosins thymalfasin, W0B22ISQ1C, alpha1 Thymosin
PubChemCID 16130571

Summary

Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Thymosin alpha-1ReviewAncell CD, Phipps J, Young L · Am J Health Syst Pharm, 2001 · PMID 11381492 · DOI
  2. Thymosin alpha-1 treatment in chronic hepatitis BEditorialResearch Support, Non-U.S. Gov'tWu X, Jia J, You H · Expert Opin Biol Ther, 2015 · PMID 25640173 · DOI
  3. Aging and Thymosin Alpha-1ReviewSimonova MA, Ivanov I, Shoshina NS et al. · Int J Mol Sci, 2025 · PMID 41373628 · DOI
  4. Thymosin alpha 1 treatment for patients with sepsisResearch Support, Non-U.S. Gov'tReviewPei F, Guan X, Wu J · Expert Opin Biol Ther, 2018 · PMID 30063866 · DOI
  5. Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacyResearch Support, Non-U.S. Gov'tLiu K, Kong L, Cui H et al. · Cell Rep Med, 2024 · PMID 39357524 · DOI
  6. Immune Modulation with Thymosin Alpha 1 TreatmentReviewKing R, Tuthill C · Vitam Horm, 2016 · PMID 27450734 · DOI
  7. Serum thymosin alpha 1 levels in normal and pathological conditionsReviewPica F, Gaziano R, Casalinuovo IA et al. · Expert Opin Biol Ther, 2018 · PMID 30063864 · DOI
  8. Clinical applications of thymosin alpha-1EditorialReviewCommentGoldstein AL · Cancer Invest, 1994 · PMID 7922712 · DOI

Top 8 of 622 results, by relevance. See all on PubMed.

Search query "thymosin alpha 1"[Title/Abstract] OR "thymalfasin"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 16130571
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaThymosin α1

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.