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Immunity

KPV (Lys-Pro-Val)

  • FormulaC16H30N4O4
  • Molecular weight342.43 g/mol
  • CAS number67727-97-3
  • PubMed results84

Reference sheet 21 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Identification

Field of researchImmunity
PubChem nameMsh (11-13)
FormulaC16H30N4O4
Molecular weight342.43 g/mol
CAS number67727-97-3
Also known asLys-pro-val, L-Lysyl-L-prolyl-L-valine, RefChem:159939, alpha-Msh (11-13), L-Valine, N-(1-L-lysyl-L-prolyl)-, ACTH-(11-13), H-Lys-Pro-Val-OH AcOH, a-MSH (11-13) (free acid), Lysyl-prolyl-valine, alpha-MSH (11-13) (free acid)
PubChemCID 125672

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human SkinResearch Support, U.S. Gov't, Non-P.H.S.Pawar K, Kolli CS, Rangari VK et al. · J Pharm Sci, 2017 · PMID 28343991 · DOI
  2. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammationResearch Support, N.I.H., ExtramuralDalmasso G, Charrier-Hisamuddin L, Nguyen HT et al. · Gastroenterology, 2008 · PMID 18061177 · DOI
  3. A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colonResearch Support, Non-U.S. Gov'tZhao Y, Xue P, Lin G et al. · Acta Biomater, 2022 · PMID 35245681 · DOI
  4. Self-Cross-Linked Hydrogel of Cysteamine-Grafted γ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in RatsResearch Support, Non-U.S. Gov'tSun J, Xue P, Liu J et al. · ACS Biomater Sci Eng, 2021 · PMID 34547895 · DOI
  5. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel diseaseComparative StudyResearch Support, Non-U.S. Gov'tKannengiesser K, Maaser C, Heidemann J et al. · Inflamm Bowel Dis, 2008 · PMID 18092346 · DOI
  6. Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptidesResearch Support, Non-U.S. Gov'tGetting SJ, Schiöth HB, Perretti M · J Pharmacol Exp Ther, 2003 · PMID 12750433 · DOI
  7. Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative ColitisXiao B, Xu Z, Viennois E et al. · Mol Ther, 2017 · PMID 28143741 · DOI
  8. Peptide Receptor-Targeted Fluorescent Probe: Visualization and Discrimination between Chronic and Acute Ulcerative ColitisZeng M, Shao A, Li H et al. · ACS Appl Mater Interfaces, 2017 · PMID 28349696 · DOI

Top 8 of 84 results, by relevance. See all on PubMed.

Search query "Lys-Pro-Val"[Title/Abstract] OR "KPV peptide"[Title/Abstract] OR "tripeptide KPV"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 125672
Published literaturePubMedSearch on PubMed

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.