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Sport and recovery

GHRP-6

Chemical compound

  • FormulaC46H56N12O6
  • Molecular weight873.0 g/mol
  • CAS number87616-84-0
  • PubMed results638

Reference sheet 15 of 40Data retrieved 2026-10-08.PubChem · PubMed · Wikipedia

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Identification

Field of researchSport and recovery
PubChem nameGrowth hormone releasing hexapeptide
FormulaC46H56N12O6
Molecular weight873.0 g/mol
CAS number87616-84-0
Also known asHexapeptide-2, Melanostatine 2, His(1)-lys(6)-ghrp, GH-Releasing hexapeptide 6, His-trp-ala-trp-phe-lysnh2, His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, Ghrp, his(1)-lys(6)-, SK&F-110679, 4H7N4I6X6A, (D-Trp(2)-D-phe(5))ghrp
PubChemCID 9919153

Summary

Growth hormone-releasing peptide 6 (GHRP-6), also known as growth hormone-releasing hexapeptide, is one of several synthetic met-enkephalin analogues that include unnatural D-amino acids, were developed for their growth hormone-releasing activity and are called growth hormone secretagogues.

From Wikipedia, available under CC BY-SA 4.0. Short description from Wikidata (CC0).

Published research

Titles are shown as published. Listing a paper is not an endorsement of its findings, and many papers on research peptides are laboratory or animal studies: the type of study is shown when PubMed records it.

  1. N-aminoimidazolidin-2-one peptidomimeticsResearch Support, Non-U.S. Gov'tDoan ND, Hopewell R, Lubell WD · Org Lett, 2014 · PMID 24697286 · DOI
  2. Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulationZhao X, Pan K, Li R et al. · J Nanobiotechnology, 2025 · PMID 41327290 · DOI
  3. Growth hormone releasing hexapeptide-6 (GHRP-6) test in the diagnosis of GH-deficiencyReviewPombo M, Leal-Cerro A, Barreiro J et al. · J Pediatr Endocrinol Metab, 1996 · PMID 8887178
  4. Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cellsResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tMcKimpson WM, Spiegel S, Mukhanova M et al. · J Cell Biol, 2024 · PMID 38958606 · DOI
  5. [D-Lys3]-GHRP-6 exhibits pro-autophagic effects on skeletal muscleResearch Support, Non-U.S. Gov'tYu AP, Pei XM, Sin TK et al. · Mol Cell Endocrinol, 2015 · PMID 25450862 · DOI
  6. Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanismsBerlanga-Acosta J, Cibrian D, Valiente-Mustelier J et al. · Front Pharmacol, 2024 · PMID 38873418 · DOI
  7. Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP-1, GHRP-2, GHRP-6, Hexarelin, and IpamorelinResearch Support, Non-U.S. Gov'tValidation StudySemenistaya E, Zvereva I, Thomas A et al. · Drug Test Anal, 2015 · PMID 25869809 · DOI
  8. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal malesReviewSinha DK, Balasubramanian A, Tatem AJ et al. · Transl Androl Urol, 2020 · PMID 32257855 · DOI

Top 8 of 638 results, by relevance. See all on PubMed.

Search query "GHRP-6"[Title/Abstract]

Data provenance

DataSourceRecord
Chemical identity and structurePubChemCID 9919153
Published literaturePubMedSearch on PubMed
Summary sentenceWikipediaGHRP-6

Data retrieved 2026-10-08. See About for the sources. How the data is collected and checked: Methods.